Head to head
Spyre Therapeutics vs Vertex Pharmaceuticals
Side-by-side on the measures that matter, with a plain-English read. Full detail: SYRE · VRTX
SYRE
Spyre Therapeutics
80.85+0.92%
1-year price shape — +405% over the period
Quant Rating B · 99/100
vs
VRTX
Vertex Pharmaceuticals
505.64+0.66%
1-year price shape — +23% over the period
Quant Rating C · 67/100
1-year performance, rebased to 100
Vertex Pharmaceuticals edges it on the scoreable measures. Vertex Pharmaceuticals earns the most per share.
| SYRE | VRTX | |
|---|---|---|
| Snapshot | ||
| Sector | Biotechnology | Biotechnology |
| Last price | 80.85 | 505.64 |
| Change today | +0.92% | +0.66% |
| 1-year return | +404.7% | +23.2% |
| Market cap | $7.13B | $128.16B |
| 52-week range | 18.12 – 110.18 | 402.58 – 560.25 |
| Valuation | ||
| P/E (TTM) | -40.83 | 29.45 |
| P/E percentile, own 5-yr range | 6th | 74th |
| P/B | 7.47 | 6.33 |
| Dividend yield | 0.00% | 0.00% |
| Profitability & growth | ||
| EPS (TTM) | -1.98 | 15.32 |
| Net profit (TTM) | $-174.58M | $3.88B |
| Revenue (TTM) | $0 | $12.59B |
| Revenue growth (YoY) | -- | +12.5% |
| Gross margin | -- | 86.0% |
| Operating margin | -22897.1% | 37.9% |
| Net margin | -52939.7% | 35.0% |
| Free cash flow (TTM) | $-208.94M | $3.80B |
| Ownership & sentiment | ||
| Institutional ownership | 110.9% | 97.2% |
| Insider activity (12mo) | 13 buy / 37 sell | 25 buy / 25 sell |
| Short interest (% of float) | 13.8% | 1.9% |
| Analyst consensus | 92% buy / 8% hold (13) | 88% buy / 8% hold / 4% sell (24) |
| Analyst price target | $122 (+51%) | $580 (+15%) |
| StockVane view | ||
| StockVane Quant Rating | B (99) | C (67) |
| Company | ||
| Employees | 102 | 6,400 |
| Founded | 2013 | 1989 |
▲ marks the more favourable stock(s) on measures with a clear direction (lower P/E, higher yield, higher Quant Rating, better 1-year return). Analyst consensus counts each covering institution once, at its most recent rating. Not a recommendation. Quant Rating method: Data & Methodology.