Spyre Therapeutics
- Market cap
- 7.13B
- P/E (TTM)i
- -40.83
- P/Bi
- 7.47
- EPSi
- -1.98
- Div yieldi
- 0.00%
- 52W posi
- 68%
Anonymous reader poll. Unscientific, not investment advice.
Spyre Therapeutics shares were changing hands at 80.85, up 0.92% on the day. The company carries a market value of roughly 7.13B, the #1646 most valuable US-listed company we track. Wall Street's 13-analyst consensus lands on Buy, with a price target averaging 122.42 (+51% from here). Over the past year the stock has ranged from 18.12 to 110.18; it now sits 68% up that band.
✦ StockVane Quant Insights how this is computed
- Twelve-month momentum in the top 1% of the universe, above its 200-day average.
- Signal has read BUY for 2 weeks.
- Its last 7 Buy calls have averaged +14% over the following quarter.
- Recent price momentum is +195.2% on average (3-month/1-year).
- Main-fund capital flow has been a net outflow over the last 45 sessions.
- Short interest has fallen to 13.8% of float.
- Analyst tilt is Buy.
- Price is below its 20-day average and below its 60-day average.
- The 20-day average is below the 60-day average, a short-term downtrend.
Computed by a StockVane algorithm from historical price, valuation and analyst data - not a person, not a forecast guarantee, and not investment advice.
Price chart
Performance
Key statistics
Price & volume
- Prev close
- 80.11
- Open
- 78.91
- Day range
- 78.00 - 82.22
- Avg price
- 80.91
- Volume
- 2.72M
- Turnover
- 220.02M
- Turnover ratei
- 3.50%
- Volume ratioi
- 1.37
- Amplitudei
- 5.27%
- 52-week rangei
- 18.12 - 110.18
Valuation
- P/Ei
- -40.83
- P/E (TTM)i
- -40.83
- P/Bi
- 7.47
- EPSi
- -1.98
- Book value / shi
- 10.83
- Net profit
- -174.58M
- Net assets
- 954.75M
Share structure
- Market cap
- 7.13B
- Float capi
- 6.27B
- Shares out
- 88.17M
- Float sharesi
- 77.61M
Dividend & listing
- Div yield (TTM)i
- 0.00%
- Dividend (TTM)
- 0.00
- Listing date
- 1970-01-01
26.6% below the 52-week high
Trading activity
Net capital flow main funds, last 45 sessions
-20.31M net over the window
Short interest
- Shares short
- 12.13M
- % of floati
- 13.76%
- Days to coveri
- 11.58
- As of
- 2026-09-15
Frequently asked questions
What is the current stock price of Spyre Therapeutics (SYRE)?
Spyre Therapeutics last traded at 80.85. The quote on this page refreshes every few seconds while US markets are open.
What is Spyre Therapeutics's market cap?
About 7.13B.
What is the P/E ratio of Spyre Therapeutics?
The trailing twelve-month P/E is -40.83. The Valuation tab shows it against the stock's own five-year range.
Does Spyre Therapeutics pay a dividend?
Spyre Therapeutics does not currently pay a regular dividend.
Is Spyre Therapeutics a buy according to analysts?
The consensus of 13 analysts is a Buy rating, with an average 12-month price target of 122.42, which implies 51.4% upside from the current price. This is not investment advice.
What is Spyre Therapeutics's StockVane Quant Rating?
The StockVane Momentum strategy currently rates Spyre Therapeutics a B (Buy). Twelve-month momentum in the top 1% of the universe, above its 200-day average. Not investment advice.
Quote time 2026-10-08 07:00:13 · For reference only, not investment advice and not tailored to your situation.