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Alnylam Pharmaceuticals

US · ALNY #627 by market cap Listed 1970
224.41 +0.47 +0.21%
Live - 5344 symbols - heartbeat 272s ago · 2026-10-08 06:56
Pre-market 221.00 -1.52%
After-hours 224.41 0.00%
Overnight 224.32 -0.04%
Market cap
30.03B
P/B
22.17
EPS
2.33
Reader sentiment Are you bullish or bearish on ALNY?

Anonymous reader poll. Unscientific, not investment advice.

Shares of Alnylam Pharmaceuticals closed at 224.41, up 0.21%. That leaves the company valued at approximately 30.03B, the #627 most valuable US-listed company we track. Valuation-wise, the P/E sits at 42.99, 136% above the five-year average of 18.21. Wall Street's 21-analyst consensus lands on Buy, with a price target averaging 369.96 (+65% from here). The shares sit 9% of the way up their 52-week range of 197.81 to 495.55.

✦ StockVane Quant Insights how this is computed

Quant Sentiment Neutral
  • Recent price momentum is -40.7% on average (3-month/1-year).
  • Main-fund capital flow has been a net inflow over the last 45 sessions.
  • Short interest has risen to 5.4% of float.
  • Analyst tilt is Buy.
Quant Technical Outlook Bearish
  • Price is below its 20-day average and below its 60-day average.
  • The 20-day average is below the 60-day average, a short-term downtrend.
Quant Rating, last 7 days C → E

Computed by a StockVane algorithm from historical price, valuation and analyst data - not a person, not a forecast guarantee, and not investment advice.

Factor grades

Ranked against 977 U.S. stocks StockVane covers.

Overall C+
ValuationGrowthProfitMomentumHealthAnalyst
Valuation D

How expensive the stock is versus earnings, sales and its own 5-year history.

P/E (TTM) 38.3x Better than 18%
Forward P/E 29.2x Better than 22%
Price / Sales 6.9x Better than 19%
P/E vs own 5-yr range 84th pctl Better than 21%
Growth N/A

How fast revenue, profit and free cash flow are compounding.

Not enough data to grade this factor.

Profitability A-

How much profit the business keeps from each dollar of sales and capital.

Gross margin 81.6% Better than 93%
Operating margin 13.5% Better than 46%
Net margin 8.4% Better than 40%
Return on equity 73.3% Better than 94%
Return on invested capital 26.3% Better than 91%
Momentum F

Recent price strength, skipping the latest month to avoid short-term noise.

3-month return -31.6% Better than 3%
6-month return -31.2% Better than 4%
12-month return (ex latest month) -41.1% Better than 4%
Distance below 52-week high 55.6% Better than 4%
Financial Health B

Balance-sheet strength: leverage, liquidity and interest coverage.

Current ratio 2.8x Better than 79%
Debt to assets 25.7% Better than 57%
Interest coverage 2.3x Better than 22%
Free cash flow / net income 148.3% Better than 72%
Analyst View A

What the Street thinks: share of Buy ratings and upside to the average target.

Analysts rating Buy 85.7% Better than 66%
Upside to average target 68.2% Better than 90%

Grades are relative rankings, not forecasts: A+ is the top 5% of the covered stocks on a factor, F the bottom 3%. Valuation is not adjusted for sector, so capital-light software tends to grade lower there than utilities. Recomputed every 6 hours from our market data. Not investment advice, and not tailored to your financial situation, goals, or risk tolerance.

Price chart

339.41205.48224.412026-04-092026-10-07
MA5MA10MA20MA60
— MA5 — MA10 — MA20 — MA60

Performance

1W -9.05%
1M -15.67%
3M -30.22%
6M -29.77%
YTD -43.57%
1Y -51.17%
3Y +26.84%
5Y +10.60%

Key statistics

Price & volume

Prev close
223.94
Open
224.39
Day range
222.46 - 230.42
Avg price
225.97
Volume
1.06M
Turnover
240.46M
Amplitude
3.56%
52-week range
197.81 - 495.55

Valuation

P/E
96.31
P/E (TTM)
39.10
P/B
22.17
EPS
2.33
Net profit
311.78M
Net assets
1.35B

Share structure

Market cap
30.03B
Float cap
29.90B
Shares out
133.81M
Float shares
133.24M

Dividend & listing

Dividend (TTM)
0.00
Listing date
1970-01-01
52-week range 9% of range
197.81 495.55

54.7% below the 52-week high

Trading activity

Net capital flow main funds, last 45 sessions

+96.23M net over the window

Short interest

Shares short
7.19M
As of
2026-09-15

Frequently asked questions

What is the current stock price of Alnylam Pharmaceuticals (ALNY)?

Alnylam Pharmaceuticals last traded at 224.41. The quote on this page refreshes every few seconds while US markets are open.

What is Alnylam Pharmaceuticals's market cap?

About 30.03B.

What is the P/E ratio of Alnylam Pharmaceuticals?

The trailing twelve-month P/E is 39.10, above its own 5-year average of 18.21 — toward the top of its historical range (84.11% percentile). See the Valuation tab for the full history.

Does Alnylam Pharmaceuticals pay a dividend?

Alnylam Pharmaceuticals does not currently pay a regular dividend.

Is Alnylam Pharmaceuticals a buy according to analysts?

The consensus of 21 analysts is a Buy rating, with an average 12-month price target of 369.96, which implies 64.9% upside from the current price. This is not investment advice.

What is Alnylam Pharmaceuticals's StockVane Quant Rating?

The StockVane Momentum strategy currently rates Alnylam Pharmaceuticals a E (Strong Sell). Below its 200-day average and near the bottom of the universe on momentum. Not investment advice.

Quote time 2026-10-08 06:56:41 · For reference only, not investment advice and not tailored to your situation.