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Axsome Therapeutics

US · AXSM #1533 by market cap Listed 2015
172.97 -1.37 -0.79%
Live - 5344 symbols - heartbeat 362s ago · 2026-10-08 05:31
Pre-market 174.31 +0.77%
After-hours 172.97 0.00%
Overnight 172.59 -0.22%
Market cap
9.06B
P/B
108.79
EPS
-3.68
Reader sentiment Are you bullish or bearish on AXSM?

Anonymous reader poll. Unscientific, not investment advice.

Valuation each multiple against its own 5-year range

P/B ratio 109.23 Expensive vs history 81st percentile
5-year average 68.92 · #510 of 514 in Biotechnology
P/E ratio -46.31 Cheap vs history 10th percentile
5-year average -21.37 · forward 344.49
P/S ratio 11.71 Cheap vs history 19th percentile
5-year average 32.05 · forward 7.58 · #171 of 388 in Biotechnology

Vs. peers Biotechnology

Company Market cap P/E (TTM) P/B Div yield
Axsome Therapeutics (AXSM) 9.06B -46.13 108.79 0.00%
Vertex Pharmaceuticals (VRTX) 128.16B 29.45 6.33 0.00%
Moderna (MRNA) 78.44B -24.62 11.60 0.00%
Regeneron Pharmaceuticals (REGN) 76.40B 18.36 2.41 0.49%
argenx SE (ARGX) 58.39B 35.37 6.94 0.00%
Revolution Medicines (RVMD) 43.05B -22.65 16.52 0.00%

Other StockVane-tracked companies in the same industry.

Morningstar

★★★☆☆ Fair value160.71 Economic moatNone UncertaintyHigh

Trading 7.1% above Morningstar's fair value estimate.

Fair value

Axsome Therapeutics Inc receives a 3-star quantitative star rating, reflecting our opinion that this share class is a balanced choice, but prudent investors should consider looking elsewhere. The stock currently trades at a 10% premium over our quantitative fair value estimate of $160.71 per share; however, this estimate should be taken with a pinch of salt due to its high uncertainty rating.

The firm's lack of profitability weakens our fair value estimate. Companies with low profitability are often less resilient in recessions and are likely to generate weaker future cash flows for shareholders. Reflecting the firm's profitability is its earnings yield of -1.2%, which lies in the bottom 30% compared with global peers. The earnings generated by the company relative to its share price is concerning, which contributes to our view that shares are overvalued.

The company's valuation metrics are an additional cause for concern. A company's valuation metrics provide insights into the market's expectations for its future growth and profitability. The firm's book value yield of 0.9%, for example, sits in the bottom 10% globally. The market value of this company's shares looks expensive relative to the book (accounting) value of equity, which further promotes our unfavorable price/fair value ratio.

In addition to the aforementioned drivers, our model considers momentum as part of its comprehensive analysis. This share class has outperformed the broader universe over the past year. This outperformance may signify a bull trap, in light of other detractors from our model.

Economic moat

With its quantitative economic moat rating of none, this business is unlikely to consistently outearn its cost of capital without structural protection from competition. Additionally, the firm's moderate financial health score suggests it is acceptably positioned against adverse economic circumstances.

By Quantitative Equity Report

Quote time 2026-10-08 05:31:53 · For reference only, not investment advice and not tailored to your situation.