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Denali Therapeutics

US · DNLI #2454 by market cap Listed 2017
19.16 -0.12 -0.62%
Live - 5344 symbols - heartbeat 195s ago · 2026-10-08 07:00
Pre-market 19.06 -0.52%
After-hours 19.16 0.00%
Overnight 19.16 0.00%
Market cap
3.06B
P/B
3.67
EPS
-2.97
Reader sentiment Are you bullish or bearish on DNLI?

Anonymous reader poll. Unscientific, not investment advice.

Valuation each multiple against its own 5-year range

P/B ratio 3.69 In line with history 65th percentile
5-year average 3.27 · #335 of 514 in Biotechnology
P/E ratio -6.79 Expensive vs history 71st percentile
5-year average -4.22 · forward -7.02
P/S ratio 855.12 In line with history 56th percentile
5-year average 972.88 · forward 32.42 · #341 of 388 in Biotechnology

Vs. peers Biotechnology

Company Market cap P/E (TTM) P/B Div yield
Denali Therapeutics (DNLI) 3.06B -6.75 3.67 0.00%
Vertex Pharmaceuticals (VRTX) 128.16B 29.45 6.33 0.00%
Moderna (MRNA) 78.44B -24.62 11.60 0.00%
Regeneron Pharmaceuticals (REGN) 76.40B 18.36 2.41 0.49%
argenx SE (ARGX) 58.39B 35.37 6.94 0.00%
Revolution Medicines (RVMD) 43.05B -22.65 16.52 0.00%

Other StockVane-tracked companies in the same industry.

Morningstar

★★★☆☆ Fair value20.26 Economic moatNone UncertaintyVery High

Trading 5.7% below Morningstar's fair value estimate.

Fair value

Denali Therapeutics Inc is assigned a 3-star quantitative star rating, reflecting our opinion that this share class is a balanced choice, but prudent investors should consider looking elsewhere. The stock currently trades at a minor 2% discount to our quantitative fair value estimate of $20.26 per share; however, caution is warranted due to this estimate's very high uncertainty rating.

The company's balance sheet bolsters our valuation estimate. Low leverage mitigates financial risk, potentially boosting a firm's value. Reflecting the firm's leverage is its current ratio of 8.4, which sits in the top 10% compared with peers globally. We have little concern about this company's ability to cover near-term obligations, thanks to its relatively high current ratio; this could be a compelling signal during times of distress, which contributes to our view that shares are cheap.

On a different note, the firm's lack of profitability is potentially concerning. Companies with low profitability are often less resilient in recessions and are likely to generate weaker future cash flows for shareholders. The firm's sales yield, a core component of profitability, lies in the bottom 1% compared with peers globally. This company's inability to generate significant sales growth without meaningful capital investment is a challenge, which, despite our favorable price/fair value ratio, is a negative attribute.

In addition to the aforementioned drivers, our model considers momentum as part of its comprehensive analysis. This share class has outperformed the broader universe over the past year. While we believe the stock is undervalued, this outperformance had a negative impact on our valuation estimate.

Economic moat

This company lacks a competitive advantage, receiving a quantitative economic moat rating of none. Additionally, the firm's moderate financial health score suggests it is acceptably positioned against adverse economic circumstances.

By Quantitative Equity Report

Quote time 2026-10-08 07:00:03 · For reference only, not investment advice and not tailored to your situation.