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Protagonist Therapeutics

US · PTGX #1570 by market cap Listed 2016
140.92 +2.23 +1.61%
Live - 5344 symbols - heartbeat 340s ago · 2026-10-08 04:39
Pre-market 141.00 +0.06%
After-hours 140.92 0.00%
Market cap
9.12B
P/B
10.84
EPS
-2.05
Reader sentiment Are you bullish or bearish on PTGX?

Anonymous reader poll. Unscientific, not investment advice.

Valuation each multiple against its own 5-year range

P/B ratio 10.75 Expensive vs history 93rd percentile
5-year average 5.15 · #447 of 514 in Biotechnology
P/E ratio 135.73 Expensive vs history 96th percentile
5-year average 13.65 · forward 28.10 · #70 of 73 in Biotechnology
P/S ratio 32.08 In line with history 58th percentile
5-year average 260.98 · forward 22.01 · #239 of 388 in Biotechnology

Vs. peers Biotechnology

Company Market cap P/E (TTM) P/B Div yield
Protagonist Therapeutics (PTGX) 9.12B 136.82 10.84 0.00%
Vertex Pharmaceuticals (VRTX) 128.16B 29.45 6.33 0.00%
Moderna (MRNA) 78.44B -24.62 11.60 0.00%
Regeneron Pharmaceuticals (REGN) 76.40B 18.36 2.41 0.49%
argenx SE (ARGX) 58.39B 35.37 6.94 0.00%
Revolution Medicines (RVMD) 43.05B -22.65 16.52 0.00%

Other StockVane-tracked companies in the same industry.

Morningstar

★★☆☆☆ Fair value125.71 Economic moatNarrow UncertaintyHigh

Trading 10.8% above Morningstar's fair value estimate.

Fair value

Protagonist Therapeutics Inc receives a 2-star quantitative star rating, illustrating our stance that this share class is a somewhat unattractive choice, and investors should look elsewhere for more fruitful opportunities. The stock currently trades at a 12% premium over our quantitative fair value estimate of $125.71 per share; however, this estimate should be taken with a pinch of salt due to its high uncertainty rating. We require the price/fair value ratio to move a certain amount before the star rating can change. This stability-enhancing buffer is in effect for this stock.

The firm's valuation metrics decrease our fair value estimate. A company's valuation metrics provide insights into the market's expectations for its future growth and profitability. Reflecting the firm's valuation is its enterprise value to EBITDA ratio of 75.6, which falls in the top 10% compared with global peers. This suggests that the value of its enterprise value, or the value of its shares and debt, is a high multiple of the generated EBITDA. We believe this is a sign that shares could be expensive.

The company's lack of profitability is an additional cause for concern. Companies with low profitability are often less resilient in recessions and are likely to generate weaker future cash flows for shareholders. The firm's sales yield of 3.0%, for example, ranks in the bottom 10% globally. This company's inability to generate significant sales growth without meaningful capital investment is a challenge, which further promotes our unfavorable price/fair value ratio.

In addition to the aforementioned drivers, our model considers momentum as part of its comprehensive analysis. This share class has outperformed the broader universe over the past year. This outperformance may signify a bull trap, in light of other detractors from our model.

Economic moat

The narrow moat rating for this company indicates investors can expect it to generate 10 years or more of excess returns on capital due to its respectable competitive advantages. In addition, the company's moderate financial health score is decent and doesn't seriously concern us with regard to financial distress.

By Quantitative Equity Report

Quote time 2026-10-08 04:39:03 · For reference only, not investment advice and not tailored to your situation.